Molecular Details
DICL_CP_0308250
- (1S,2R)-2-[(S)-amino(carboxy)methyl]cyclopropane-1-carboxylic acid
Basic Molecular Information
Basic Information
DICL ID
DICL_CP_0308250
PubChem CID
Molecular Formula
C6H9NO4 Molecular Weight
159.141 g/mol
Synonyms/Alias
[L-CCG-IV; 117857-95-1; (2S;3R;4S)-CCG; 117857-96-2; (1S;2R)-2-[(S)-AMINO(CARBOXY)METHYL]CYCLOPROPANE-1-CARBOXYLIC ACID; CHEMBL282842; (2s;3r;4s)-alpha-(carboxycyclopropyl)glycine; L-CCG III; (1S;2R)-...
InChI Key
GZOVEPYOCJWRFC-UZBSEBFBSA-N
InChI
InChI=1S/C6H9NO4/c7-4(6(10)11)2-1-3(2)5(8)9/h2-4H,1,7H2,(H,8,9)(H,10,11)/t2-,3+,4+/m1/s1
IUPAC Name
(1S,2R)-2-[(S)-amino(carboxy)methyl]cyclopropane-1-carboxylic acid
CAS Number
147782-19-2
Structure Information
Chemical Structure Visualization
SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF
11 11 0 0 0 0 0 0 0 0999 V2000
-0.5879 -1.7124 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
0.0527 -0.3561 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-1.4423 -0...
Experimental Data
Activity Data
Target Ion Channel
Glutamate receptor ionotropic subunit NMDA 1/2A
Uniprot Accession Number
Function
Potentiator
Species
Homo sapiens (Human)
IC50
N/A (Not available)
EC50
EC50: 262 nM
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)
Experimental Conditions
pH
pH 7.4
Holding Potential
−40 mV mV
Temperature
23 °C
Test Method
Patch-clamping
Test Species
Xenopus laevis oocyte
Binding Information
Binding Site
Not specified
Binding Site Residue
Not specified
Disease Information
Related Disease
Not specified
References
Computed Properties
Heavy Atom Count
11
Rotatable Bonds
3
logP
-0.881
Complexity
34.844
TPSA (Ų)
100.62
H-Bond Donors
3
H-Bond Acceptors
3
Ring Count
1